PDB entry 1lyb

View 1lyb on RCSB PDB site
Description: crystal structures of native and inhibited forms of human cathepsin d: implications for lysosomal targeting and drug design
Deposited on 1993-04-22, released 1994-01-31
The last revision prior to the SCOP 1.57 freeze date was dated 1994-01-31, with a file datestamp of 1994-01-31.
Experiment type: -
Resolution: 2.5 Å
R-factor: 0.179
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Domains in SCOP 1.57: d1lyb.1
  • Chain 'B':
    Domains in SCOP 1.57: d1lyb.1
  • Chain 'C':
    Domains in SCOP 1.57: d1lyb.2
  • Chain 'D':
    Domains in SCOP 1.57: d1lyb.2

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lybA (A:)
gpipevlknymdaqyygeigigtppqcftvvfdtgssnlwvpsihcklldiacwihhkyn
sdksstyvkngtsfdihygsgslsgylsqdtvsvpcq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lybB (B:)
ggvkverqvfgeatkqpgitfiaakfdgilgmayprisvnnvlpvfdnlmqqklvdqnif
sfylsrdpdaqpggelmlggtdskyykgslsylnvtrkaywqvhldqvevasgltlckeg
ceaivdtgtslmvgpvdevrelqkaigavpliqgeymipcekvstlpaitlklggkgykl
spedytlkvsqagktlclsgfmgmdipppsgplwilgdvfigryytvfdrdnnrvgfaea
a

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lybC (C:)
gpipevlknymdaqyygeigigtppqcftvvfdtgssnlwvpsihcklldiacwihhkyn
sdksstyvkngtsfdihygsgslsgylsqdtvsvpcq

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lybD (D:)
ggvkverqvfgeatkqpgitfiaakfdgilgmayprisvnnvlpvfdnlmqqklvdqnif
sfylsrdpdaqpggelmlggtdskyykgslsylnvtrkaywqvhldqvevasgltlckeg
ceaivdtgtslmvgpvdevrelqkaigavpliqgeymipcekvstlpaitlklggkgykl
spedytlkvsqagktlclsgfmgmdipppsgplwilgdvfigryytvfdrdnnrvgfaea
a