PDB entry 1kr3

View 1kr3 on RCSB PDB site
Description: Crystal Structure of the Metallo beta-Lactamase from Bacteroides fragilis (CfiA) in Complex with the Tricyclic Inhibitor SB-236050.
Class: hydrolase
Keywords: beta sandwich, protein-inhibitor complex, metallo, beta-lactamase, HYDROLASE
Deposited on 2002-01-08, released 2003-01-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.152
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase, type II
    Species: Bacteroides fragilis [TaxId:817]
    Gene: CfiA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1kr3a_
  • Chain 'B':
    Compound: beta-lactamase, type II
    Species: Bacteroides fragilis [TaxId:817]
    Gene: CfiA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1kr3b_
  • Heterogens: ZN, NA, 113, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kr3A (A:)
aqksvkisddisitqlsdkvytyvslaeiegwgmvpsngmivinnhqaalldtpindaqt
emlvnwvtdslhakvttfipnhwhgdcigglgylqrkgvqsyanqmtidlakekglpvpe
hgftdsltvsldgmplqcyylggghatdnivvwlptenilfggcmlkdnqatsignisda
dvtawpktldkvkakfpsaryvvpghgdyggteliehtkqivnqyiestskp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kr3A (A:)
svkisddisitqlsdkvytyvslaeiegwgmvpsngmivinnhqaalldtpindaqteml
vnwvtdslhakvttfipnhwhgdcigglgylqrkgvqsyanqmtidlakekglpvpehgf
tdsltvsldgmplqcyylggghatdnivvwlptenilfggcmlkdnqatsignisdadvt
awpktldkvkakfpsaryvvpghgdyggteliehtkqivnqyiests

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kr3B (B:)
aqksvkisddisitqlsdkvytyvslaeiegwgmvpsngmivinnhqaalldtpindaqt
emlvnwvtdslhakvttfipnhwhgdcigglgylqrkgvqsyanqmtidlakekglpvpe
hgftdsltvsldgmplqcyylggghatdnivvwlptenilfggcmlkdnqatsignisda
dvtawpktldkvkakfpsaryvvpghgdyggteliehtkqivnqyiestskp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kr3B (B:)
svkisddisitqlsdkvytyvslaeiegwgmvpsngmivinnhqaalldtpindaqteml
vnwvtdslhakvttfipnhwhgdcigglgylqrkgvqsyanqmtidlakekglpvpehgf
tdsltvsldgmplqcyylggghatdnivvwlptenilfggcmlkdnqatsignisdadvt
awpktldkvkakfpsaryvvpghgdyggteliehtkqivnqyiests