PDB entry 1k8q

View 1k8q on RCSB PDB site
Description: crystal structure of dog gastric lipase in complex with a phosphonate inhibitor
Class: hydrolase
Keywords: apha beta hydrolase fold, hydrolase
Deposited on 2001-10-25, released 2002-03-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.197
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Triacylglycerol lipase, gastric
    Species: Canis lupus [TaxId:9615]
    Gene: LIPF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80035 (0-376)
      • conflict (0)
      • conflict (191)
    Domains in SCOPe 2.06: d1k8qa_
  • Chain 'B':
    Compound: Triacylglycerol lipase, gastric
    Species: Canis lupus [TaxId:9615]
    Gene: LIPF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80035 (0-376)
      • conflict (0)
      • conflict (191)
    Domains in SCOPe 2.06: d1k8qb_
  • Heterogens: NAG, BOG, C11, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1k8qA (A:)
    afgklhptnpevtmnisqmitywgypaeeyevvtedgyilgidripygrknsenigrrpv
    aflqhgllasatnwisnlpnnslafiladagydvwlgnsrgntwarrnlyyspdsvefwa
    fsfdemakydlpatidfilkktgqdklhyvghsqgttigfiafstnpklakriktfyala
    pvatvkytetlinklmlvpsflfklifgnkifyphhffdqflatevcsretvdllcsnal
    fiicgfdtmnlnmsrldvylshnpagtsvqnvlhwsqavksgkfqafdwgspvqnmmhyh
    qsmppyynltdmhvpiavwnggndlladphdvdlllsklpnliyhrkippynhldfiwam
    dapqavyneivsmmgtd
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1k8qB (B:)
    afgklhptnpevtmnisqmitywgypaeeyevvtedgyilgidripygrknsenigrrpv
    aflqhgllasatnwisnlpnnslafiladagydvwlgnsrgntwarrnlyyspdsvefwa
    fsfdemakydlpatidfilkktgqdklhyvghsqgttigfiafstnpklakriktfyala
    pvatvkytetlinklmlvpsflfklifgnkifyphhffdqflatevcsretvdllcsnal
    fiicgfdtmnlnmsrldvylshnpagtsvqnvlhwsqavksgkfqafdwgspvqnmmhyh
    qsmppyynltdmhvpiavwnggndlladphdvdlllsklpnliyhrkippynhldfiwam
    dapqavyneivsmmgtd