PDB entry 1jew

View 1jew on RCSB PDB site
Description: cryo-em structure of coxsackievirus b3(m strain) with its cellular receptor, coxsackievirus and adenovirus receptor (car).
Class: Virus/Receptor
Keywords: COXSACKIEVIRUS B3, CVB3, CAR, CRYO-EM STRUCTURE, Icosahedral virus, Virus/Receptor COMPLEX
Deposited on 2001-06-19, released 2001-10-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-06.
Experiment type: EM
Resolution: 22 Å
R-factor: N/A
AEROSPACI score: -0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: coxsackievirus capsid, coat protein vp1
    Species: Coxsackievirus B3 (strain Woodruff) [TaxId:103904]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1jew1_
  • Chain '2':
    Compound: coxsackievirus capsid, coat protein vp2
    Species: Coxsackievirus B3 (strain Woodruff) [TaxId:103904]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q66282 (Start-262)
      • conflict (150)
      • conflict (244)
    Domains in SCOPe 2.04: d1jew2_
  • Chain '3':
    Compound: coxsackievirus capsid, coat protein vp3
    Species: Coxsackievirus B3 (strain Woodruff) [TaxId:103904]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q66282 (0-237)
      • conflict (233)
    Domains in SCOPe 2.04: d1jew3_
  • Chain '4':
    Compound: coxsackievirus capsid, coat protein vp4
    Species: Coxsackievirus B3 (strain Woodruff) [TaxId:103904]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1jew4_
  • Chain 'R':
    Compound: coxsackievirus and adenovirus receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: CAR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1jewr_

PDB Chain Sequences:

  • Chain '1':
    Sequence, based on SEQRES records: (download) 
    >1jew1 (1:)
gpvedaitaaigrvadtvgtgptnseaipaltaaetghtsqvvpsdtmqtrhvknyhsrs
estienflcrsacvyfteyensgakryaewvitprqaaqlrrklefftyvrfdleltfvi
tstqqpsttqnqdaqilthqimyvppggpvpdkvdsyvwqtstnpsvfwtegnapprmsv
pflsignaysnfydgwsefsrngvygintlnnmgtlyarhvnagstgpikstiriyfkpk
hvkawiprpprlcqyekaknvnfqpsgvtttrqsittmtnt

    Sequence, based on observed residues (ATOM records): (download) 
    >1jew1 (1:)
rvadtvgtgptnseaipaltaaetghtsqvvpsdtmqtrhvknyhsrsestienflcrsa
cvyfteyensgakryaewvitprqaaqlrrklefftyvrfdleltfvitstqqpsttqnq
daqilthqimyvppggpvpdkvdsyvwqtstnpsvfwtegnapprmsvpflsignaysnf
ydgwsefsrngvygintlnnmgtlyarhvnagstgpikstiriyfkpkhvkawiprpprl
cqyekaknvnfqpsgvtttrqsittmtnt

  • Chain '2':
    Sequence, based on SEQRES records: (download) 
    >1jew2 (2:)
sptveecgysdrvrsitlgnstittqecanvvvgygvwpdylkdseataedqptqpdvat
crfytldsvqwqktspgwwwklpdalsnlglfgqnmqyhylgrtgytihvqcnaskfhqg
cllvvcvpeaemgcatlnntpssaellggdtakefadkpvasgsnklvqrvvynagmgvg
vgnltifphqwinlrtnnsativmpytnsvpmdnmfrhnnvtlmvipfvpldycpgstty
vpitvtiapmcaeynglrlaghq

    Sequence, based on observed residues (ATOM records): (download) 
    >1jew2 (2:)
gysdrvrsitlgnstittqecanvvvgygvwpdylkdseataedqptqpdvatcrfytld
svqwqktspgwwwklpdalsnlglfgqnmqyhylgrtgytihvqcnaskfhqgcllvvcv
peaemgcatlnntpssaellggdtakefadkpvasgsnklvqrvvynagmgvgvgnltif
phqwinlrtnnsativmpytnsvpmdnmfrhnnvtlmvipfvpldycpgsttyvpitvti
apmcaeynglrlaghq

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1jew3 (3:)
glptmntpgscqfltsddfqspsampqydvtpemripgevknlmeiaevdsvvpvqnvge
kvnsmeayqipvrsnegsgtqvfgfplqpgyssvfsrtllgeilnyythwsgsikltfmf
cgsamatgkfllaysppgagaptkrvdamlgthvvwdvglqsscvlcipwisqthyryva
sdeytaggfitcwyqtnivvpadaqsscyimcfvsacndfsvrllkdtpfisqenffq

  • Chain '4':
    Sequence, based on SEQRES records: (download) 
    >1jew4 (4:)
gaqvstqktgahetglnasgnsiihytninyykdaasnsanrqdftqdpskftepvkdim
ikslpaln

    Sequence, based on observed residues (ATOM records): (download) 
    >1jew4 (4:)
gaqvstqktgihytninyykdaasnsanrqdftqdpskftepvkdimikslpaln

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1jewR (R:)
sittpeemiekakgetaylpckftlspedqgpldiewlispadnqkvdqviilysgdkiy
ddyypdlkgrvhftsndlksgdasinvtnlqlsdigtyqckvkkapgvankkihlvvlvk