PDB entry 1ibw

View 1ibw on RCSB PDB site
Description: structure of the d53,54n mutant of histidine decarboxylase bound with histidine methyl ester at 25 c
Class: lyase
Keywords: substrate-induced activation, active form, site-directed mutant, pyruvoyl, carboxy-lyase, lyase
Deposited on 2001-03-29, released 2002-03-13
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.204
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: histidine decarboxylase beta chain
    Species: Lactobacillus sp. [TaxId:1593]
    Gene: HDCA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00862 (0-80)
      • engineered (52-53)
    Domains in SCOPe 2.04: d1ibw.1
  • Chain 'B':
    Compound: histidine decarboxylase alpha chain
    Species: Lactobacillus sp. [TaxId:1593]
    Gene: HDCA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1ibw.1
  • Chain 'C':
    Compound: histidine decarboxylase beta chain
    Species: Lactobacillus sp. [TaxId:1593]
    Gene: HDCA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00862 (0-80)
      • engineered (52-53)
    Domains in SCOPe 2.04: d1ibw.2
  • Chain 'D':
    Compound: histidine decarboxylase alpha chain
    Species: Lactobacillus sp. [TaxId:1593]
    Gene: HDCA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1ibw.2
  • Chain 'E':
    Compound: histidine decarboxylase beta chain
    Species: Lactobacillus sp. [TaxId:1593]
    Gene: HDCA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00862 (0-80)
      • engineered (52-53)
    Domains in SCOPe 2.04: d1ibw.3
  • Chain 'F':
    Compound: histidine decarboxylase alpha chain
    Species: Lactobacillus sp. [TaxId:1593]
    Gene: HDCA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1ibw.3
  • Heterogens: PYR, PVH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ibwA (A:)
seldaklnklgvdriaispykqwtrgymepgnigngyvtglkvdagvrdksdnnvldgiv
sydraetknayigqinmttas

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ibwB (B:)
ftgvqgrvigydilrspevdkakplftetqwdgselpiydakplqdalveyfgteqdrrh
ypapgsfivcankgvtaerpkndadmkpgqgygvwsaiaisfakdptkdssmfvedagvw
etpnedelleylegrrkamaksiaecgqdahasfesswigfaytmmepgqignaitvapy
vslpidsipggsiltpdkdmeimenltmpewlekmgykslsannalky

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ibwC (C:)
seldaklnklgvdriaispykqwtrgymepgnigngyvtglkvdagvrdksdnnvldgiv
sydraetknayigqinmttas

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ibwD (D:)
ftgvqgrvigydilrspevdkakplftetqwdgselpiydakplqdalveyfgteqdrrh
ypapgsfivcankgvtaerpkndadmkpgqgygvwsaiaisfakdptkdssmfvedagvw
etpnedelleylegrrkamaksiaecgqdahasfesswigfaytmmepgqignaitvapy
vslpidsipggsiltpdkdmeimenltmpewlekmgykslsannalky

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ibwE (E:)
seldaklnklgvdriaispykqwtrgymepgnigngyvtglkvdagvrdksdnnvldgiv
sydraetknayigqinmttas

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ibwF (F:)
ftgvqgrvigydilrspevdkakplftetqwdgselpiydakplqdalveyfgteqdrrh
ypapgsfivcankgvtaerpkndadmkpgqgygvwsaiaisfakdptkdssmfvedagvw
etpnedelleylegrrkamaksiaecgqdahasfesswigfaytmmepgqignaitvapy
vslpidsipggsiltpdkdmeimenltmpewlekmgykslsannalky