PDB entry 1i85
View 1i85 on RCSB PDB site
Description: crystal structure of the ctla-4/b7-2 complex
Class: immune system
Keywords: Ig V-type domain, IMMUNE SYSTEM
Deposited on
2001-03-12, released
2001-04-04
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.217
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: t lymphocyte activation antigen cd86
Species: Homo sapiens [TaxId:9606]
Gene: CD86
Database cross-references and differences (RAF-indexed):
- Uniprot P42081 (1-109)
- initiating methionine (0)
Domains in SCOPe 2.04: d1i85a_ - Chain 'B':
Compound: t lymphocyte activation antigen cd86
Species: Homo sapiens [TaxId:9606]
Gene: CD86
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1i85b_ - Chain 'C':
Compound: cytotoxic t-lymphocyte-associated protein 4
Species: Homo sapiens [TaxId:9606]
Gene: CTLA4
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1i85c_ - Chain 'D':
Compound: cytotoxic t-lymphocyte-associated protein 4
Species: Homo sapiens [TaxId:9606]
Gene: CTLA4
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1i85d_
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1i85A (A:)
mlkiqayfnetadlpcqfansqnqslselvvfwqdqenlvlnevylgkekfdsvhskymg
rtsfdsdswtlrlhnlqikdkglyqciihhkkptgmirihqmnselsvla
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1i85B (B:)
mlkiqayfnetadlpcqfansqnqslselvvfwqdqenlvlnevylgkekfdsvhskymg
rtsfdsdswtlrlhnlqikdkglyqciihhkkptgmirihqmnselsvla
Sequence, based on observed residues (ATOM records): (download)
>1i85B (B:)
lkiqayfnetadlpcqfansqnqslselvvfwqdqenlvlnevylgkekfdsvhskymgr
tsfdsdswtlrlhnlqikdkglyqciihhkkptgmirihqmnselsvla
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1i85C (C:)
kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
pcpdsd
Sequence, based on observed residues (ATOM records): (download)
>1i85C (C:)
mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
- Chain 'D':
Sequence, based on SEQRES records: (download)
>1i85D (D:)
kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
pcpdsd
Sequence, based on observed residues (ATOM records): (download)
>1i85D (D:)
mhvaqpavvlassrgiasfvceyaatevrvtvlrqqvtevcaatymmgneltflddsict
gtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe