PDB entry 1hwg

View 1hwg on RCSB PDB site
Description: 1:2 complex of human growth hormone with its soluble binding protein
Class: complex (hormone/receptor)
Keywords: cytokine, hormone, receptor, hematopoietic, complex (hormone/receptor)
Deposited on 1996-11-13, released 1997-11-19
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.199
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: growth hormone
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1hwga_
  • Chain 'B':
    Compound: growth hormone binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1hwgb1, d1hwgb2
  • Chain 'C':
    Compound: growth hormone binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1hwgc1, d1hwgc2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hwgA (A:)
fptiplsrlfdnamlrahrlhqlafdtyqefeeayipkeqkysflqnpqtslcfsesipt
psnreetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
iqtlmgrledgsprtgqifkqtyskfdtnshnddallknygllycfrkdmdkvetflriv
qcrsvegscgf

    Sequence, based on observed residues (ATOM records): (download) 
    >1hwgA (A:)
fptiplsrlfdnamlrahrlhqlafdtyqefeeayipkeqkysflqnpqtslcfsesipt
psnreetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
iqtlmgrledgsprtgqifkqtyskfddallknygllycfrkdmdkvetflrivqcrsve
gscg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hwgB (B:)
fsgseataailsrapwslqsvnpglktnsskepkftkcrsperetfschwtdevhhgtkn
lgpiqlfytrrntqewtqewkecpdyvsagenscyfnssftsiwipycikltsnggtvde
kcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadiqkgwmvleyelqyke
vnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygefsevlyvtlpqms

    Sequence, based on observed residues (ATOM records): (download) 
    >1hwgB (B:)
epkftkcrsperetfschwtdepiqlfytrrntqewtqewkecpdyvsagenscyfnssf
tsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrweap
rnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsg
nygefsevlyvtlp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1hwgC (C:)
fsgseataailsrapwslqsvnpglktnsskepkftkcrsperetfschwtdevhhgtkn
lgpiqlfytrrntqewtqewkecpdyvsagenscyfnssftsiwipycikltsnggtvde
kcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadiqkgwmvleyelqyke
vnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygefsevlyvtlpqms

    Sequence, based on observed residues (ATOM records): (download) 
    >1hwgC (C:)
epkftkcrsperetfschwtdpiqlfytrrnqewkecpdyvsagenscyfnssftsiwip
ycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadiq
kgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygefs
evlyvtlpqms