SCOPe 2.07: Structural Classification of Proteins

PDB entry 1hrt

View 1hrt on RCSB PDB site
Description: the structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8 angstroms resolution
Class: hydrolase(serine proteinase)
Keywords: hydrolase(serine proteinase)
Deposited on 1993-02-25, released 1994-01-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.155
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

Chain 'H':
Compound: thrombin (large subunit)
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00735 (0-258)
Domains in SCOPe 2.07: d1hrt.1
Chain 'I':
Compound: hirudin
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Uniprot P01050 (0-64)
Domains in SCOPe 2.07: d1hrti_
Chain 'L':
Compound: thrombin (small subunit)
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00735 (Start-48)
Domains in SCOPe 2.07: d1hrt.1
Heterogens: HOH

PDB Chain Sequences:

Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)

>1hrtH (H:)
ivegqdaevglspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftvddll
vrigkhsrtryerkvekismldkiyihprynwkenldrdiallklkrpielsdyihpvcl
pdkqtaakllhagfkgrvtgwgnrretwttsvaevqpsvlqvvnlplverpvckastrir
itdnmfcagykpgegkrgdacegdsggpfvmkspynnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidrlgs

Chain 'I':
Sequence; same for both SEQRES and ATOM records: (download)

>1hrtI (I:)
vvytdctesgqnlclcegsnvcgqgnkcilgsdgeknqcvtgegtpkpqshndgdfeeip
eeylq

Chain 'L':
Sequence, based on SEQRES records: (download)
```
>1hrtL (L:)
tsedhfqpffnektfgageadcglrplfekkqvqdqtekelfesyiegr
```
Sequence, based on observed residues (ATOM records): (download)
```
>1hrtL (L:)
tfgageadcglrplfekkqvqdqtekelfesyiegr
```