PDB entry 1hjc

View 1hjc on RCSB PDB site
Description: crystal structure of runx-1/aml1/cbfalpha runt domain bound to a DNA fragment from the csf-1r promoter
Class: transcription/DNA
Keywords: transcription/DNA, protein-DNA complex, transcription factor, bzip, runx, runt, c/ebp, cbf, core binding factor, aml1, aml, oncoprotein
Deposited on 2001-01-11, released 2001-03-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.223
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: runt-related transcription factor 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hjca_
  • Chain 'B':
    Compound: DNA (5'-(*gp*ap*ap*cp*tp*cp*tp*gp*tp*gp*gp* tp*tp*gp*cp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'C':
    Compound: DNA (5'-(cp*cp*gp*cp*ap*ap*cp*cp*ap*cp*ap* gp*ap*gp*tp*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'D':
    Compound: runt-related transcription factor 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hjcd_
  • Chain 'E':
    Compound: DNA (5'-(*gp*ap*ap*cp*tp*cp*tp*gp*tp*gp*gp* tp*tp*gp*cp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'F':
    Compound: DNA (5'-(cp*cp*gp*cp*ap*ap*cp*cp*ap*cp*ap* gp*ap*gp*tp*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hjcA (A:)
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgpreprrh
rqk

    Sequence, based on observed residues (ATOM records): (download) 
    >1hjcA (A:)
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgprepr

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hjcD (D:)
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgpreprrh
rqk

    Sequence, based on observed residues (ATOM records): (download) 
    >1hjcD (D:)
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgprepr

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.