PDB entry 1hai
View 1hai on RCSB PDB site
Description: the isomorphous structures of prethrombin2, hirugen-and ppack-thrombin: changes accompanying activation and exosite binding to thrombin
Class: HYDROLASE/hydrolase inhibitor
Keywords: SERINE PROTEINASE, HYDROLASE-hydrolase inhibitor complex
Deposited on
1994-06-27, released
1994-12-20
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.139
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: alpha-thrombin (large subunit)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1hai.1 - Chain 'L':
Compound: alpha-thrombin (small subunit)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1hai.1 - Heterogens: 0G6, NAG, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>1haiH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1haiH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwgqpsvlqvvnlpiverpvckdstriritdnmf
cagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrl
kkwiqkvidqfge
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1haiL (L:)
tfgsgeadcglrplfekksledkterellesyidgr