PDB entry 1h6f

View 1h6f on RCSB PDB site
Description: human tbx3, a transcription factor responsible for ulnar-mammary syndrome , bound to a palindromic DNA site
Class: transcription factor
Keywords: transcription factor, tbx3, t-box transcription factor, ulnar-mammary syndrome, holt-oram-syndrome, ig-fold, DNA-binding, repressor, nuclear protein, developmental protein
Deposited on 2001-06-13, released 2002-04-19
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.2007
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: t-box transcription factor tbx3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1h6fa_
  • Chain 'B':
    Compound: t-box transcription factor tbx3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1H6F
    • Uniprot O15119 (2-End)
    Domains in SCOPe 2.02: d1h6fb_
  • Chain 'C':
    Compound: 5'-d(*tp*ap*ap*tp*tp*tp*cp*ap*cp*ap*cp*cp*tp* ap*gp*gp*tp*gp*tp*gp*ap*ap*ap*t)-3'
    Species: synthetic, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: 5'-d(*tp*ap*ap*tp*tp*tp*cp*ap*cp*ap*cp*cp*tp* ap*gp*gp*tp*gp*tp*gp*ap*ap*ap*t)-3'
    Species: synthetic, synthetic [TaxId:32630]
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h6fA (A:)
mkddpkvhleakelwdqfhkrgtemvitksgrrmfppfkvrcsgldkkakyillmdiiaa
ddcrykfhnsrwmvagkadpempkrmyihpdspatgeqwmskvvtfhklkltnnisdkhg
ftilnsmhkyqprfhivrandilklpystfrtylfpetefiavtayqndkitqlkidnnp
fakgfrdtgngrr

    Sequence, based on observed residues (ATOM records): (download) 
    >1h6fA (A:)
dpkvhleakelwdqfhkrgtemvitksgrrmfppfkvrcsgldkkakyillmdiiaaddc
rykfhnsrwmvagkadpempkrmyihpdspatgeqwmskvvtfhklkltnnisdkhgfti
lnsmhkyqprfhivrandilklpystfrtylfpetefiavtayqndkitqlkidnnpfak
gfrd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1h6fB (B:)
mkddpkvhleakelwdqfhkrgtemvitksgrrmfppfkvrcsgldkkakyillmdiiaa
ddcrykfhnsrwmvagkadpempkrmyihpdspatgeqwmskvvtfhklkltnnisdkhg
ftilnsmhkyqprfhivrandilklpystfrtylfpetefiavtayqndkitqlkidnnp
fakgfrdtgngrr

    Sequence, based on observed residues (ATOM records): (download) 
    >1h6fB (B:)
kddpkvhleakelwdqfhkrgtemvitksgrrmfppfkvrcsgldkkakyillmdiiaad
dcrykfhnsrwmvagkadpempkrmyihpdspatgeqwmskvvtfhklkltnnisdkhgf
tilnsmhkyqprfhivrandilklpystfrtylfpetefiavtayqndkitqlkidnnpf
akgfrd

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.