PDB entry 1gko

View 1gko on RCSB PDB site
Description: an engineered transthyretin monomer that is non-amyloidogenic - unless partially denatured
Class: transport(thyroxine)
Keywords: transport(thyroxine), transthyretin, ttr, mutant monomer transthyretin, mutant monomer ttr, amyloid forming protein, amyloid
Deposited on 2001-08-17, released 2001-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.2067
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (86)
      • engineered mutation (109)
    Domains in SCOPe 2.07: d1gkoa_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (86)
      • engineered mutation (109)
    Domains in SCOPe 2.07: d1gkob_
  • Chain 'C':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (86)
      • engineered mutation (109)
    Domains in SCOPe 2.07: d1gkoc_
  • Chain 'D':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (86)
      • engineered mutation (109)
    Domains in SCOPe 2.07: d1gkod_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gkoA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkoA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvtn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gkoB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkoB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1gkoC (C:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkoC (C:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvtn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1gkoD (D:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkoD (D:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvt