PDB entry 1gbh

View 1gbh on RCSB PDB site
Description: alpha-lytic protease with met 190 replaced by ala and gly 216 replaced by leu complex with methoxysuccinyl-ala-ala-pro-leucine boronic acid
Class: hydrolase/hydrolase inhibitor
Keywords: active-site mutation, serine proteinase, hydrolase-hydrolase inhibitor complex
Deposited on 1995-09-06, released 1996-01-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.149
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-lytic protease
    Species: Lysobacter enzymogenes [TaxId:69]
    Gene: ALPHA-LYTIC PROTEASE PREPROENZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00778 (Start-197)
      • engineered (137)
      • engineered (160)
    Domains in SCOPe 2.07: d1gbha_
  • Chain 'P':
    Compound: methoxysuccinyl-ala-ala-pro-leucine boronic acid inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 1GBH (Start-4)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gbhA (A:)
anivggieysinnaslcsvgfsvtrgatkgfvtaghcgtvnatariggavvgtfaarvfp
gndrawvsltsaqtllprvangssfvtvrgsteaavgaavcrsgrttgyqcgtitaknvt
anyaegavrgltqgnacagrgdsggswitsagqaqgvmsglnvqsngnncgipasqrssl
ferlqpilsqyglslvtg

  • Chain 'P':
    No sequence available.