PDB entry 1g4u

View 1g4u on RCSB PDB site
Description: crystal structure of the salmonella tyrosine phosphatase and gtpase activating protein sptp bound to rac1
Class: signaling protein
Keywords: virulence factor, GAP, tyrosine phosphatase, 4-helix bundle, GTPase, SIGNALING PROTEIN
Deposited on 2000-10-28, released 2001-01-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'R':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAC1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63000 (0-End)
      • engineered (77)
    Domains in SCOPe 2.08: d1g4ur_
  • Chain 'S':
    Compound: protein tyrosine phosphatase sptp
    Species: Salmonella typhimurium [TaxId:602]
    Gene: SPTP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1g4us1, d1g4us2
  • Heterogens: MG, GDP, AF3, HOH

PDB Chain Sequences:

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >1g4uR (R:)
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
pvkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1g4uR (R:)
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >1g4uS (S:)
ndvgaeskqplldialkglkrtlpqleqmdgnslrenfqemasgngplrslmtnlqnlnk
ipeakqlndyvttltniqvgvarfsqwgtcggeverwvdkastheltqavkkihviakel
knvtaelekieagapmpqtmsgptlglarfavssipinqqtqvklsdgmpvpvntltfdg
kpvalagsypkntpdaleahmkmllekecsclvvltsedqmqakqlppyfrgsytfgevh
tnsqkvssasqgeaidqynmqlscgekrytipvlhvknwpdhqplpstdqleyladrvkn
snqngapgrsssdkhlpmihclggvgrtgtmaaalvlkdnphsnleqvradfrdsrnnrm
ledasqfvqlkamqaqllmttas

    Sequence, based on observed residues (ATOM records): (download) 
    >1g4uS (S:)
skqplldialkglkrtlpqleqmdgnslrenfqemasgngplrslmtnlqnlnkipeakq
lndyvttltniqvgvarfsqwgtcggeverwvdkastheltqavkkihviakelknvtae
lekieagapmpqtmsgptlglarfavssipinqqtqvklsdgmpvpvntltfdgkpvala
gsypkntpdaleahmkmllekecsclvvltsedqmqakqlppyfrgsytfgevhtnsqkv
ssasqgeaidqynmqlscgekrytipvlhvknwpdhqplpstdqleyladrvknkhlpmi
hclggvgrtgtmaaalvlkdnphsnleqvradfrdsrnnrmledasqfvqlkamqaqllm