SCOPe 2.08: Structural Classification of Proteins

PDB entry 1fsk

View 1fsk on RCSB PDB site
Description: complex formation between a fab fragment of a monoclonal igg antibody and the major allergen from birch pollen bet v 1
Class: immune system
Keywords: Bet v 1, Bv16 Fab fragment, antibody allergen complex, IMMUNE SYSTEM
Deposited on 2000-09-11, released 2000-10-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-07, with a file datestamp of 2018-03-02.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: major pollen allergen bet v 1-a
Species: Betula pendula [TaxId:3505]
Database cross-references and differences (RAF-indexed):
- Uniprot P15494 (0-158)
Domains in SCOPe 2.08: d1fska_
Chain 'B':
Compound: immunoglobulin kappa light chain
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- Uniprot P01837 (0-213)
  - conflict (3)
  - conflict (12)
  - conflict (21)
  - conflict (29)
  - conflict (33)
  - conflict (35)
  - conflict (40)
  - conflict (47)
  - conflict (50)
  - conflict (67)
  - conflict (90)
  - conflict (148)
Domains in SCOPe 2.08: d1fskb1, d1fskb2
Chain 'C':
Compound: antibody heavy chain fab
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- PDB 1FSK (0-219)
Domains in SCOPe 2.08: d1fskc1, d1fskc2, d1fskc3
Chain 'D':
Compound: major pollen allergen bet v 1-a
Species: Betula pendula [TaxId:3505]
Database cross-references and differences (RAF-indexed):
- Uniprot P15494 (0-158)
Domains in SCOPe 2.08: d1fskd_
Chain 'E':
Compound: immunoglobulin kappa light chain
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- Uniprot P01837 (0-213)
  - conflict (3)
  - conflict (12)
  - conflict (21)
  - conflict (29)
  - conflict (33)
  - conflict (35)
  - conflict (40)
  - conflict (47)
  - conflict (50)
  - conflict (67)
  - conflict (90)
  - conflict (148)
Domains in SCOPe 2.08: d1fske1, d1fske2
Chain 'F':
Compound: antibody heavy chain fab
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- PDB 1FSK (0-219)
Domains in SCOPe 2.08: d1fskf1, d1fskf2, d1fskf3
Chain 'G':
Compound: major pollen allergen bet v 1-a
Species: Betula pendula [TaxId:3505]
Database cross-references and differences (RAF-indexed):
- Uniprot P15494 (0-158)
Domains in SCOPe 2.08: d1fskg_
Chain 'H':
Compound: immunoglobulin kappa light chain
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- Uniprot P01837 (0-213)
  - conflict (3)
  - conflict (12)
  - conflict (21)
  - conflict (29)
  - conflict (33)
  - conflict (35)
  - conflict (40)
  - conflict (47)
  - conflict (50)
  - conflict (67)
  - conflict (90)
  - conflict (148)
Domains in SCOPe 2.08: d1fskh1, d1fskh2
Chain 'I':
Compound: antibody heavy chain fab
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- PDB 1FSK (0-219)
Domains in SCOPe 2.08: d1fski1, d1fski2, d1fski3
Chain 'J':
Compound: major pollen allergen bet v 1-a
Species: Betula pendula [TaxId:3505]
Database cross-references and differences (RAF-indexed):
- Uniprot P15494 (0-158)
Domains in SCOPe 2.08: d1fskj_
Chain 'K':
Compound: immunoglobulin kappa light chain
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- Uniprot P01837 (0-213)
  - conflict (3)
  - conflict (12)
  - conflict (21)
  - conflict (29)
  - conflict (33)
  - conflict (35)
  - conflict (40)
  - conflict (47)
  - conflict (50)
  - conflict (67)
  - conflict (90)
  - conflict (148)
Domains in SCOPe 2.08: d1fskk1, d1fskk2
Chain 'L':
Compound: antibody heavy chain fab
Species: Mus musculus [TaxId:10090]
Gene: BALB/C MICE
Database cross-references and differences (RAF-indexed):
- PDB 1FSK (0-219)
Domains in SCOPe 2.08: d1fskl1, d1fskl2, d1fskl3

PDB Chain Sequences:

Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskA (A:)
gvfnyetettsvipaarlfkafildgdnlfpkvapqaissveniegnggpgtikkisfpe
glpfkyvkdrvdevdhtnfkynysvieggpigdtlekisneikivatpdggsilkisnky
htkgdhevkaeqvkaskemgetllravesyllahsdayn

Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskB (B:)
nivltqspksmsvsvgervtlsckasenvdtyvfwfqqkpdqspklllygpsnrytgvpd
rftgsgsttdftltissvqaedladyhcgqsysypytfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskC (C:)
qvqlqqpgtelvrpgasvilsckasgytftsywinwvkqrpgqglewvgnifpsdsytny
nqkfkdkatltvdkssstaymqvnsptsedsavyyctrgardtwfaywgqgtlvtvsvak
ttppsvfplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskD (D:)
gvfnyetettsvipaarlfkafildgdnlfpkvapqaissveniegnggpgtikkisfpe
glpfkyvkdrvdevdhtnfkynysvieggpigdtlekisneikivatpdggsilkisnky
htkgdhevkaeqvkaskemgetllravesyllahsdayn

Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskE (E:)
nivltqspksmsvsvgervtlsckasenvdtyvfwfqqkpdqspklllygpsnrytgvpd
rftgsgsttdftltissvqaedladyhcgqsysypytfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskF (F:)
qvqlqqpgtelvrpgasvilsckasgytftsywinwvkqrpgqglewvgnifpsdsytny
nqkfkdkatltvdkssstaymqvnsptsedsavyyctrgardtwfaywgqgtlvtvsvak
ttppsvfplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

Chain 'G':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskG (G:)
gvfnyetettsvipaarlfkafildgdnlfpkvapqaissveniegnggpgtikkisfpe
glpfkyvkdrvdevdhtnfkynysvieggpigdtlekisneikivatpdggsilkisnky
htkgdhevkaeqvkaskemgetllravesyllahsdayn

Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskH (H:)
nivltqspksmsvsvgervtlsckasenvdtyvfwfqqkpdqspklllygpsnrytgvpd
rftgsgsttdftltissvqaedladyhcgqsysypytfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

Chain 'I':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskI (I:)
qvqlqqpgtelvrpgasvilsckasgytftsywinwvkqrpgqglewvgnifpsdsytny
nqkfkdkatltvdkssstaymqvnsptsedsavyyctrgardtwfaywgqgtlvtvsvak
ttppsvfplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

Chain 'J':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskJ (J:)
gvfnyetettsvipaarlfkafildgdnlfpkvapqaissveniegnggpgtikkisfpe
glpfkyvkdrvdevdhtnfkynysvieggpigdtlekisneikivatpdggsilkisnky
htkgdhevkaeqvkaskemgetllravesyllahsdayn

Chain 'K':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskK (K:)
nivltqspksmsvsvgervtlsckasenvdtyvfwfqqkpdqspklllygpsnrytgvpd
rftgsgsttdftltissvqaedladyhcgqsysypytfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)

>1fskL (L:)
qvqlqqpgtelvrpgasvilsckasgytftsywinwvkqrpgqglewvgnifpsdsytny
nqkfkdkatltvdkssstaymqvnsptsedsavyyctrgardtwfaywgqgtlvtvsvak
ttppsvfplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc