PDB entry 1fap
View 1fap on RCSB PDB site
Description: the structure of the immunophilin-immunosuppressant fkbp12-rapamycin complex interacting with human frap
Class: complex (isomerase/kinase)
Keywords: fkbp12, frap, rapamycin, complex (isomerase/kinase)
Deposited on
1996-03-15, released
1997-07-23
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.193
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: fk506-binding protein
Species: Homo sapiens [TaxId:9606]
Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1fapa_ - Chain 'B':
Compound: frap
Species: Homo sapiens [TaxId:9606]
Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1fapb_ - Heterogens: RAP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1fapA (A:)
gvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgwe
egvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1fapB (B:)
rvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrd
lmeaqewcrkymksgnvkdltqawdlyyhvfrris