PDB entry 1esm

View 1esm on RCSB PDB site
Description: structural basis for the feedback regulation of escherichia coli pantothenate kinase by coenzyme a
Class: transferase
Keywords: protein-inhibitor complex, transferase
Deposited on 2000-04-10, released 2000-09-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.201
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pantothenate kinase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6I3 (Start-315)
      • modified residue (8)
      • modified residue (28)
      • modified residue (141)
      • modified residue (152)
      • modified residue (207)
      • modified residue (274)
    Domains in SCOPe 2.07: d1esma_
  • Chain 'B':
    Compound: pantothenate kinase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6I3 (Start-315)
      • modified residue (8)
      • modified residue (28)
      • modified residue (141)
      • modified residue (152)
      • modified residue (207)
      • modified residue (274)
    Domains in SCOPe 2.07: d1esmb_
  • Chain 'C':
    Compound: pantothenate kinase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6I3 (Start-315)
      • modified residue (8)
      • modified residue (28)
      • modified residue (141)
      • modified residue (152)
      • modified residue (207)
      • modified residue (274)
    Domains in SCOPe 2.07: d1esmc_
  • Chain 'D':
    Compound: pantothenate kinase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6I3 (Start-315)
      • modified residue (8)
      • modified residue (28)
      • modified residue (141)
      • modified residue (152)
      • modified residue (207)
      • modified residue (274)
    Domains in SCOPe 2.07: d1esmd_
  • Heterogens: COA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1esmA (A:)
msikeqtlmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsr
llnfyissnlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrr
velittdgflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliy
dvipdgdktvvqpdilileglnvlqsgmdyphdphhvfvsdfvdfsiyvdapedllqtwy
inrflkfregaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasli
ltksanhaveevrlrk

    Sequence, based on observed residues (ATOM records): (download) 
    >1esmA (A:)
qtlmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsrllnfy
issnlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrrvelit
tdgflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliydvipd
gdktvvqpdilileglnvlqsgmdyphdphhvfvsdfvdfsiyvdapedllqtwyinrfl
kfregaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasliltksa
nhaveevrlrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1esmB (B:)
msikeqtlmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsr
llnfyissnlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrr
velittdgflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliy
dvipdgdktvvqpdilileglnvlqsgmdyphdphhvfvsdfvdfsiyvdapedllqtwy
inrflkfregaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasli
ltksanhaveevrlrk

    Sequence, based on observed residues (ATOM records): (download) 
    >1esmB (B:)
lmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsrllnfyis
snlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrrvelittd
gflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliydvipdgd
ktvvqpdilileglnvlqsgmdydphhvfvsdfvdfsiyvdapedllqtwyinrflkfre
gaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasliltksanhav
eevrlrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1esmC (C:)
msikeqtlmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsr
llnfyissnlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrr
velittdgflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliy
dvipdgdktvvqpdilileglnvlqsgmdyphdphhvfvsdfvdfsiyvdapedllqtwy
inrflkfregaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasli
ltksanhaveevrlrk

    Sequence, based on observed residues (ATOM records): (download) 
    >1esmC (C:)
qtlmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsrllnfy
issnlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrrvelit
tdgflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliydvipd
gdktvvqpdilileglnvlqsgmdphhvfvsdfvdfsiyvdapedllqtwyinrflkfre
gaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasliltksanhav
eevrlrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1esmD (D:)
msikeqtlmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsr
llnfyissnlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrr
velittdgflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliy
dvipdgdktvvqpdilileglnvlqsgmdyphdphhvfvsdfvdfsiyvdapedllqtwy
inrflkfregaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasli
ltksanhaveevrlrk

    Sequence, based on observed residues (ATOM records): (download) 
    >1esmD (D:)
lmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsrllnfyis
snlrrqavleqflgtripyiisiagsvavgksttarvlqallsrwpehrrvelittdgfl
hpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliydvipdgdktv
vqpdilileglnvlqsgmdyphhvfvsdfvdfsiyvdapedllqtwyinrflkfregaft
dpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasliltksanhaveevr
lrk