PDB entry 1eq2

View 1eq2 on RCSB PDB site
Description: the crystal structure of ADP-l-glycero-d-mannoheptose 6-epimerase
Class: isomerase
Keywords: N-terminal domain Rossmann fold, C-terminal mixed alpha/beta domain, Short-chain dehydrogenase/reductase fold, ISOMERASE
Deposited on 2000-03-31, released 2000-11-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.212
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2a_
  • Chain 'B':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2b_
  • Chain 'C':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2c_
  • Chain 'D':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2d_
  • Chain 'E':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2e_
  • Chain 'F':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2f_
  • Chain 'G':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2g_
  • Chain 'H':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2h_
  • Chain 'I':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2i_
  • Chain 'J':
    Compound: ADP-l-glycero-d-mannoheptose 6-epimerase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67910 (0-End)
      • modified residue (77)
    Domains in SCOPe 2.06: d1eq2j_
  • Heterogens: NAP, ADQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1eq2A (A:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2A (A:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnnkrdfvyvgdvadvnlwflengvsgifnlgtgraesfqavadatyqa
    ftqadltnlraagydkpfktvaegvteymawln
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1eq2B (B:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2B (B:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfyqaftqadltnlraagydkpfktvaegvteymawln
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1eq2C (C:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2C (C:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnfkrdfvyvgdvadvnlwflengvsgifnlgtgraesfqavadayqaf
    tqadltnlraagydkpfktvaegvteymawln
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1eq2D (D:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2D (D:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawln
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1eq2E (E:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2E (E:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfyqaftqadltnlraagydkpfktvaegvteymawln
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1eq2F (F:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2F (F:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawln
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1eq2G (G:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2G (G:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawln
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1eq2H (H:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2H (H:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyyqaftqadltnlraagydkpfktvaegvteymawln
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1eq2I (I:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2I (I:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawln
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >1eq2J (J:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvt
    eymawlnrda
    

    Sequence, based on observed residues (ATOM records): (download)
    >1eq2J (J:)
    miivtggagfigsnivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqi
    mageefgdveaifhegacssttewdgkymmdnnyqyskellhyclereipflyassaaty
    ggrtsdfiesreyekplnvygyskflfdeyvrqilpeansqivgfryfnvygpreghkgs
    masvafhlntqlnngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgra
    esfqavadatlayhkkgqieyipfyqaftqadltnlraagydkpfktvaegvteymawln