PDB entry 1ecv
View 1ecv on RCSB PDB site
Description: crystal structure of protein tyrosine phosphatase 1b complexed with 5-iodo-2-(oxalyl-amino)-benzoic acid
Class: hydrolase
Keywords: hydrolase, phosphorylation, ligand, inhibitor
Deposited on
2000-01-26, released
2000-03-15
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.194
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein-tyrosine phosphatase 1b
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P18031 (Start-297)
- conflict (150)
- conflict (251)
Domains in SCOPe 2.02: d1ecva_ - Heterogens: ACT, 878, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1ecvA (A:)
memekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklh
qedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslk
caqywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwp
dfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkd
pssvdikkvlldmrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshed
Sequence, based on observed residues (ATOM records): (download)
>1ecvA (A:)
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdp
ssvdikkvlldmrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshed