SCOP 1.59: Structural Classification of Proteins

PDB entry 1dia

View 1dia on RCSB PDB site
Description: human methylenetetrahydrofolate dehydrogenase / cyclohydrolase complexed with nadp and inhibitor ly249543
Deposited on 1999-11-29, released 2000-07-05
The last revision prior to the SCOP 1.59 freeze date was dated 2000-07-05, with a file datestamp of 2000-07-05.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.227
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Domains in SCOP 1.59: d1diaa1, d1diaa2
Chain 'B':
Domains in SCOP 1.59: d1diab1, d1diab2

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>1diaA (A:)
apaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaae
eigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiape
kdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapm
hdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginyv
pddkkpngrkvvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrfle

Sequence, based on observed residues (ATOM records): (download)

>1diaA (A:)
apaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaae
eigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiape
kdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapm
hdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginyk
vvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrfle

Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)

>1diaB (B:)
apaeilngkeisaqirarlknqvtqlkeqvpgftprlailqvgnrddsnlyinvklkaae
eigikathiklprtttesevmkyitslnedstvhgflvqlpldsensinteevinaiape
kdvdgltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapm
hdlllwnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginyv
pddkkpngrkvvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrfle