PDB entry 1c0g

View 1c0g on RCSB PDB site
Description: crystal structure of 1:1 complex between gelsolin segment 1 and a dictyostelium/tetrahymena chimera actin (mutant 228: q228k/t229a/a230y/e360h)
Class: contractile protein
Keywords: actin mutant, contractile protein
Deposited on 1999-07-16, released 2000-03-01
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: -1.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (chimeric actin)
    Species: Dictyostelium discoideum, Tetrahymena thermophila [TaxId:44689,5911]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07830 (0-374)
      • modified residue (72)
      • conflict (224)
      • see remark 999 (227-229)
      • see remark 999 (359)
    Domains in SCOPe 2.04: d1c0ga1, d1c0ga2
  • Chain 'S':
    Compound: protein (gelsolin segment 1)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06396 (3-126)
      • expression artifact (0-2)
    Domains in SCOPe 2.04: d1c0gs_
  • Heterogens: CA, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1c0gA (A:)
dgedvqalvidngsgmckagfagddapravfpsivgrprhtgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvshtvpiyegyalphailrldl
agrdltdymmkiltergysftttaereivrdikeklayvaldfeaemkayasssaleksy
elpdgqvitignerfrcpealfqpsflgmesagihettynsimkcdvdirkdlygnvvls
ggttmfpgiadrmnkeltalapstmkikiiapperkysvwiggsilaslstfqqmwiskh
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >1c0gA (A:)
dgedvqalvidngsgmckagfagddapravfpsivgrprhtgkdsyvgdeaqskrgiltl
kypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfetf
ntpamyvaiqavlslyasgrttgivmdsgdgvshtvpiyegyalphailrldlagrdltd
ymmkiltergysftttaereivrdikeklayvaldfeaemkayasssaleksyelpdgqv
itignerfrcpealfqpsflgmesagihettynsimkcdvdirkdlygnvvlsggttmfp
giadrmnkeltalapstmkikiiapperkysvwiggsilaslstfqqmwiskheydesgp
sivhrkcf

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1c0gS (S:)
mgsvvehpeflkagkepglqiwrvekfdlvpvptclygdfftgdayvilktvqlrngnlq
ydlhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykk
ggvasgf