PDB entry 1a9c

View 1a9c on RCSB PDB site
Description: GTP cyclohydrolase I (c110s mutant) in complex with GTP
Class: hydrolase
Keywords: hydrolase, GTP, purine hydrolysis, pterine synthesis, tetrahydrobiopterin
Deposited on 1998-04-04, released 1999-05-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.206
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9ca_
  • Chain 'B':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cb_
  • Chain 'C':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cc_
  • Chain 'D':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cd_
  • Chain 'E':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9ce_
  • Chain 'F':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cf_
  • Chain 'G':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cg_
  • Chain 'H':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9ch_
  • Chain 'I':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9ci_
  • Chain 'J':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cj_
  • Chain 'K':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9ck_
  • Chain 'L':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cl_
  • Chain 'M':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cm_
  • Chain 'N':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9cn_
  • Chain 'O':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • mutation (109)
    Domains in SCOPe 2.07: d1a9co_
  • Heterogens: GTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cA (A:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cB (B:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cC (C:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cD (D:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cE (E:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cF (F:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cG (G:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cH (H:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cI (I:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cJ (J:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cK (K:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cL (L:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cM (M:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cN (N:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a9cO (O:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstsehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn