Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 proteins) parent family to TK and PFOR heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module |
Protein Branched-chain alpha-keto acid dehydrogenase, PP module [88767] (2 species) |
Species Thermus thermophilus [TaxId:274] [102337] (4 PDB entries) |
Domain d1umda_: 1umd A: [99599] Other proteins in same PDB: d1umdb1, d1umdb2, d1umdd1, d1umdd2 complexed with coi, mg, tdp |
PDB Entry: 1umd (more details), 1.9 Å
SCOPe Domain Sequences for d1umda_:
Sequence; same for both SEQRES and ATOM records: (download)
>d1umda_ c.36.1.11 (A:) Branched-chain alpha-keto acid dehydrogenase, PP module {Thermus thermophilus [TaxId: 274]} hrfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilirtgkts fiapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatkadpnkg rqmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatsegdwya ginfaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdvlasyy vvkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprfrrfle arglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqeallke el
Timeline for d1umda_: