Lineage for d1t2ea2 (1t2e A:164-331)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1938734Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 1938735Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 1938736Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 1938743Protein Lactate dehydrogenase [56339] (18 species)
  7. 1938897Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [56343] (13 PDB entries)
  8. 1938905Domain d1t2ea2: 1t2e A:164-331 [99087]
    Other proteins in same PDB: d1t2ea1
    complexed with gol, nai, oxm; mutant

Details for d1t2ea2

PDB Entry: 1t2e (more details), 1.85 Å

PDB Description: Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate
PDB Compounds: (A:) l-lactate dehydrogenase

SCOPe Domain Sequences for d1t2ea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1t2ea2 d.162.1.1 (A:164-331) Lactate dehydrogenase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
ggvldtsrlkyyisqklnvcprdvnahivgahgnkmvllkryitvggiplqefinnklis
daeleaifdrtvntaleivnlhaapyvapaaaiiemaesylkdlkkvlicstllegqygh
sdifggtpvvlgangveqvielqlnseekakfdeaiaetkrmkplahh

SCOPe Domain Coordinates for d1t2ea2:

Click to download the PDB-style file with coordinates for d1t2ea2.
(The format of our PDB-style files is described here.)

Timeline for d1t2ea2:

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Domains from same chain:
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d1t2ea1