Lineage for d1s26b_ (1s26 B:)

  1. Root: SCOPe 2.08
  2. 3012399Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)
  3. 3020281Fold e.41: Adenylylcyclase toxin (the edema factor) [81299] (1 superfamily)
    3 domains: (1&2) alpha+beta, with domain 2 being inserted in domain 1; (3) all-alpha
  4. 3020282Superfamily e.41.1: Adenylylcyclase toxin (the edema factor) [81298] (1 family) (S)
    Domain 1 has topological and active site similarity to the Nucleotidyltransferases (eg. 1kny N-domain); domain 3 binds calmodulin
  5. 3020283Family e.41.1.1: Adenylylcyclase toxin (the edema factor) [69887] (1 protein)
    decorated with many insertions and the C-terminal domain
  6. 3020284Protein Adenylylcyclase toxin (the edema factor) [69888] (1 species)
  7. 3020285Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [69889] (7 PDB entries)
    Uniprot P40136
  8. 3020294Domain d1s26b_: 1s26 B: [98368]
    Other proteins in same PDB: d1s26d_, d1s26e_, d1s26f_
    complexed with apc, ca, yb

Details for d1s26b_

PDB Entry: 1s26 (more details), 3 Å

PDB Description: structure of anthrax edema factor-calmodulin-alpha,beta- methyleneadenosine 5'-triphosphate complex reveals an alternative mode of atp binding to the catalytic site
PDB Compounds: (B:) calmodulin-sensitive adenylate cyclase

SCOPe Domain Sequences for d1s26b_:

Sequence, based on SEQRES records: (download)

>d1s26b_ e.41.1.1 (B:) Adenylylcyclase toxin (the edema factor) {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtnll
ikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdnei
fiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkak
intiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhifs
qekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksnief
kllykqlnftenetdnfevfqkiid

Sequence, based on observed residues (ATOM records): (download)

>d1s26b_ e.41.1.1 (B:) Adenylylcyclase toxin (the edema factor) {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnekqkgvtnllik
ygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdneifi
inpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkakin
tipsvkkiagylsdyynsanhifsqekkrkisifrgiqayneienvlkskqiapeyknyf
qylkeritnqvqlllthqkfkllykqlnftenetdnfevfqkiid

SCOPe Domain Coordinates for d1s26b_:

Click to download the PDB-style file with coordinates for d1s26b_.
(The format of our PDB-style files is described here.)

Timeline for d1s26b_: