SCOP 1.67: Domain d1rzgd2: 1rzg D:108-214

Lineage for d1rzgd2 (1rzg D:108-214)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (22 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (22 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (74 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)

8. Domain d1rzgd2: 1rzg D:108-214 [98161]
   Other proteins in same PDB: d1rzga1, d1rzga2, d1rzgb1, d1rzgc1, d1rzgc2, d1rzgd1
   part of anti HIV-1 gp120-reactive Fab 412D
   complexed with suc

Details for d1rzgd2

PDB Entry: 1rzg, 2 Å

PDB Description: crystal structure of human anti-hiv-1 gp120 reactive antibody 412d

SCOP Domain Sequences for d1rzgd2:

Sequence; same for both SEQRES and ATOM records:

>d1rzgd2 b.1.1.2 (D:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens)}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhklyacevthqglsspvtksfnrgec

Timeline for d1rzgd2:

• d1rzgd2 is new in SCOP 1.67
  
• d1rzgd2 appears in SCOP 1.69
  
• d1rzgd2 appears in the current release, SCOPe 2.08