Lineage for d1rz7h1 (1rz7 H:1-113)

  1. Root: SCOP 1.69
  2. 450777Class b: All beta proteins [48724] (144 folds)
  3. 450778Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 450779Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 450780Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)
  6. 450916Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 450971Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88544] (16 PDB entries)
  8. 450975Domain d1rz7h1: 1rz7 H:1-113 [98133]
    Other proteins in same PDB: d1rz7h2, d1rz7l1, d1rz7l2
    part of anti HIV-1 gp120-reactive Fab 48D

Details for d1rz7h1

PDB Entry: 1rz7 (more details), 2 Å

PDB Description: crystal structure of human anti-hiv-1 gp120-reactive antibody 48d

SCOP Domain Sequences for d1rz7h1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rz7h1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 1}
evqlvqsgaevkkpgatvkisckasgytfsdfymywvrqapgkglewmglidpedadtmy
aekfrgrvtitadtstdtgylelsslrsedtavyycaadpwelnafnvwgqgtlvsvss

SCOP Domain Coordinates for d1rz7h1:

Click to download the PDB-style file with coordinates for d1rz7h1.
(The format of our PDB-style files is described here.)

Timeline for d1rz7h1:

View in 3D
Domains from same chain:
(mouse over for more information)
d1rz7h2