Lineage for d1rukh1 (1ruk H:1-113)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 546556Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 547188Species Mouse (Mus musculus), cluster 7.1 [TaxId:10090] [88557] (34 PDB entries)
  8. 547190Domain d1rukh1: 1ruk H:1-113 [97859]
    Other proteins in same PDB: d1rukh2, d1rukl1, d1rukl2
    part of cationic cyclization catalytic Fab 4C6
    complexed with act, bez, gol

Details for d1rukh1

PDB Entry: 1ruk (more details), 1.4 Å

PDB Description: Crystal structure (C) of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 9-1

SCOP Domain Sequences for d1rukh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rukh1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 7.1}

SCOP Domain Coordinates for d1rukh1:

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Timeline for d1rukh1:

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