SCOPe 2.01: Domain d1rdqe_: 1rdq E:

Lineage for d1rdqe_ (1rdq E:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein cAMP-dependent PK, catalytic subunit [56116] (4 species)
   AGC group; PKA subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56119] (24 PDB entries)

8. Domain d1rdqe_: 1rdq E: [97314]
   complexed with peptide inhibitor, chain B
   complexed with adp, atp, gol, mg, mrd, po4; mutant

Details for d1rdqe_

PDB Entry: 1rdq, 1.26 Å

PDB Description: hydrolysis of atp in the crystal of y204a mutant of camp-dependent protein kinase

PDB Compounds: (E:) cAMP-dependent protein kinase, alpha-catalytic subunit

SCOPe Domain Sequences for d1rdqe_:

Sequence, based on SEQRES records:

>d1rdqe_ d.144.1.7 (E:) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
qvtdfgfakrvkgrtwtlcgtpealapeiilskgynkavdwwalgvliyemaagyppffa
dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfatt
dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

Sequence, based on observed residues (ATOM records):

>d1rdqe_ d.144.1.7 (E:) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
gnaaasvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnh
yamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggem
fshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfa
krvkgrtwtlcgtpealapeiilskgynkavdwwalgvliyemaagyppffadqpiqiye
kivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqr
kveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

Timeline for d1rdqe_:

• d1rdqe_ first appeared in SCOP 1.67
  
• d1rdqe_ appears in SCOP 1.75
  
• d1rdqe_ appears in SCOPe 2.02
  
• d1rdqe_ appears in the current release, SCOPe 2.08