SCOPe 2.04: Domain d1rcja_: 1rcj A:

Lineage for d1rcja_ (1rcj A:)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)

6. Protein beta-Lactamase, class A [56606] (16 species)

7. Species Klebsiella pneumoniae, SHV-1 [TaxId:573] [56609] (23 PDB entries)
   inhibited by tazobactam
   Uniprot Q5PSW7 ! Uniprot P14557 22-286

8. Domain d1rcja_: 1rcj A: [97293]
   complexed with ma4, tbi; mutant

Details for d1rcja_

PDB Entry: 1rcj, 1.63 Å

PDB Description: crystal structure of e166a mutant of shv-1 beta-lactamase with the trans-enamine intermediate of tazobactam

PDB Compounds: (A:) Beta-lactamase SHV-1

SCOPe Domain Sequences for d1rcja_:

Sequence; same for both SEQRES and ATOM records:

>d1rcja_ e.3.1.1 (A:) beta-Lactamase, class A {Klebsiella pneumoniae, SHV-1 [TaxId: 573]}
spqpleqiklsesqlsgrvgmiemdlasgrtltawraderfpmmstfkvvlcgavlarvd
agdeqlerkihyrqqdlvdyspvsekhladgmtvgelcaaaitmsdnsaanlllatvggp
agltaflrqigdnvtrldrwatelnealpgdardtttpasmaatlrklltsqrlsarsqr
qllqwmvddrvagplirsvlpagwfiadktgagergargivallgpnnkaerivviylrd
tpasmaernqqiagigaaliehwqr

Timeline for d1rcja_:

• d1rcja_ first appeared in SCOP 1.67
  
• d1rcja_ appears in SCOPe 2.03
  
• d1rcja_ appears in SCOPe 2.05
  
• d1rcja_ appears in the current release, SCOPe 2.08