SCOPe 2.03: Domain d1r46a1: 1r46 A:324-421

Lineage for d1r46a1 (1r46 A:324-421)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.71: Glycosyl hydrolase domain [51010] (1 superfamily)
   folded sheet; greek-key

4. Superfamily b.71.1: Glycosyl hydrolase domain [51011] (6 families)
   this domain is C-terminal to the catalytic beta/alpha barrel domain

5. Family b.71.1.1: alpha-Amylases, C-terminal beta-sheet domain [51012] (22 proteins)
   this domain follows the catalytic beta/alpha barrel domain

6. Protein Melibiase [75020] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101919] (11 PDB entries)
   alpha-galactosidase A

8. Domain d1r46a1: 1r46 A:324-421 [96973]
   Other proteins in same PDB: d1r46a2, d1r46b2
   complexed with edo, nag

Details for d1r46a1

PDB Entry: 1r46, 3.25 Å

PDB Description: structure of human alpha-galactosidase

PDB Compounds: (A:) Alpha-galactosidase A

SCOPe Domain Sequences for d1r46a1:

Sequence; same for both SEQRES and ATOM records:

>d1r46a1 b.71.1.1 (A:324-421) Melibiase {Human (Homo sapiens) [TaxId: 9606]}
lgkqgyqlrqgdnfevwerplsglawavaminrqeiggprsytiavaslgkgvacnpacf
itqllpvkrklgfyewtsrlrshinptgtvllqlentm

Timeline for d1r46a1:

• d1r46a1 first appeared in SCOP 1.67
  
• d1r46a1 appears in SCOPe 2.02
  
• d1r46a1 appears in SCOPe 2.04
  
• d1r46a1 appears in the current release, SCOPe 2.08