Lineage for d1r1wa_ (1r1w A:)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 734668Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 734669Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 734710Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 735223Protein Hepatocyte growth factor receptor, c-MET [103300] (1 species)
    PTK group; HGFR subfamily; membrane spanning protein tyrosine kinase
  7. 735224Species Human (Homo sapiens) [TaxId:9606] [103301] (2 PDB entries)
  8. 735226Domain d1r1wa_: 1r1w A: [96833]
    mutant

Details for d1r1wa_

PDB Entry: 1r1w (more details), 1.8 Å

PDB Description: crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-met
PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOP Domain Sequences for d1r1wa_:

Sequence, based on SEQRES records: (download)

>d1r1wa_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
tvhidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcav
kslnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfi
rnethnptvkdligfglqvakgmkflaskkfvhrdlaarncmldekftvkvadfglardm
ydkefdsvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvnt
fditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehy
vhvnatyvnvk

Sequence, based on observed residues (ATOM records): (download)

>d1r1wa_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
tvhidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtllkihcavkslnr
itdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirneth
nptvkdligfglqvakgmkflaskkfvhrdlaarncmldekftvkvadfglardmylpvk
wmaleslqtqkfttksdvwsfgvllwelmtrgappypditvyllqgrrllqpeycpdply
evmlkcwhpkaemrpsfselvsrisaifstfigehyvhvnatyvnvk

SCOP Domain Coordinates for d1r1wa_:

Click to download the PDB-style file with coordinates for d1r1wa_.
(The format of our PDB-style files is described here.)

Timeline for d1r1wa_: