SCOP 1.67: Domain d1r0xa_: 1r0x A:

Lineage for d1r0xa_ (1r0x A:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (22 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.12: ABC transporter ATPase domain-like [52686] (16 proteins)
   there are two additional subdomains inserted into the central core that has a RecA-like topology

6. Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [102379] (6 PDB entries)

8. Domain d1r0xa_: 1r0x A: [96758]

Details for d1r0xa_

PDB Entry: 1r0x, 2.2 Å

PDB Description: cystic fibrosis transmembrane conductance regulator (cftr) nucleotide- binding domain one (nbd1) with atp

SCOP Domain Sequences for d1r0xa_:

Sequence, based on SEQRES records:

>d1r0xa_ c.37.1.12 (A:) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Mouse (Mus musculus)}
tgiimenvtafweegfgellekvqqsngdrkhssdennvsfshlclvgnpvlkninlnie
kgemlaitgstgsgktsllmlilgeleasegiikhsgrvsfcsqfswimpgtikeniifg
vsydeyryksvvkacqlqqditkfaeqdntvlgeggvtlsggqrarislaravykdadly
lldspfgyldvfteeqvfescvcklmanktrilvtskmehlrkadkililhqgssyfygt
fselqslrpdfssklmgydtfdqfteerrssiltetlrrfs

Sequence, based on observed residues (ATOM records):

>d1r0xa_ c.37.1.12 (A:) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Mouse (Mus musculus)}
tgiimenvtafweegfgelleksfshlclvgnpvlkninlniekgemlaitgstgsgkts
llmlilgeleasegiikhsgrvsfcsqfswimpgtikeniifgvsydeyryksvvkacql
qqditkfaeqdntvlgeggvtlsggqrarislaravykdadlylldspfgyldvfteeqv
fescvcklmanktrilvtskmehlrkadkililhqgssyfygtfselqslrpdfssklmg
ydtfdqfteerrssiltetlrrfs

Timeline for d1r0xa_:

• d1r0xa_ is new in SCOP 1.67
  
• d1r0xa_ appears in SCOP 1.69
  
• d1r0xa_ appears in the current release, SCOPe 2.08