SCOPe 2.06: Domain d1qxec_: 1qxe C:

Lineage for d1qxec_ (1qxe C:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.1: Globin-like [46457] (2 superfamilies)
   core: 6 helices; folded leaf, partly opened

4. Superfamily a.1.1: Globin-like [46458] (5 families)

5. Family a.1.1.2: Globins [46463] (27 proteins)
   Heme-binding protein

6. Protein Hemoglobin, alpha-chain [46486] (24 species)

7. Species Human (Homo sapiens) [TaxId:9606] [46487] (253 PDB entries)
   Uniprot P69905 P01922 P01934 P01935

8. Domain d1qxec_: 1qxe C: [96525]
   Other proteins in same PDB: d1qxeb_, d1qxed_
   complexed with fux, hem, oxy, so4

Details for d1qxec_

PDB Entry: 1qxe, 1.85 Å

PDB Description: structural basis for the potent antisickling effect of a novel class of 5-membered heterocyclic aldehydic compounds

PDB Compounds: (C:) hemoglobin alpha chain

SCOPe Domain Sequences for d1qxec_:

Sequence; same for both SEQRES and ATOM records:

>d1qxec_ a.1.1.2 (C:) Hemoglobin, alpha-chain {Human (Homo sapiens) [TaxId: 9606]}
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

Timeline for d1qxec_:

• d1qxec_ first appeared in SCOP 1.67
  
• d1qxec_ appears in SCOPe 2.05
  
• d1qxec_ appears in SCOPe 2.07
  
• d1qxec_ appears in the current release, SCOPe 2.08