SCOP 1.75: Domain d1q9ob1: 1q9o B:1-111

Lineage for d1q9ob1 (1q9o B:1-111)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (47 PDB entries)
   Uniprot P01796 #
   HV27_MOUSE Ig heavy chain V-III region A4
   Uniprot P01796 # ! HV27_MOUSE Ig heavy chain V-III region A4

8. Domain d1q9ob1: 1q9o B:1-111 [96294]
   Other proteins in same PDB: d1q9oa1, d1q9oa2, d1q9ob2, d1q9oc1, d1q9oc2, d1q9od2
   part of Fab s45-18

Details for d1q9ob1

PDB Entry: 1q9o, 1.79 Å

PDB Description: S45-18 Fab Unliganded

PDB Compounds: (B:) S45-2 Fab (IgG1k) heavy chain

SCOP Domain Sequences for d1q9ob1:

Sequence; same for both SEQRES and ATOM records:

>d1q9ob1 b.1.1.1 (B:1-111) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 1 [TaxId: 10090]}
evilvesggglvqpggslrlscstsgftftdyymswvrqppgkalewlgfirnkpkgytt
eysasvkgrftisrdnsqsilylqmntlraedsatyycvrdiysfgsrdgmdywgqgtsv
tvss

Timeline for d1q9ob1:

• d1q9ob1 first appeared in SCOP 1.67
  
• d1q9ob1 appears in SCOP 1.73
  
• d1q9ob1 appears in SCOPe 2.01
  
• d1q9ob1 appears in the current release, SCOPe 2.08