SCOPe 2.01: Domain d1q9lb1: 1q9l B:1-111

Lineage for d1q9lb1 (1q9l B:1-111)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (46 PDB entries)
   Uniprot P01796 # ! HV27_MOUSE Ig heavy chain V-III region A4

8. Domain d1q9lb1: 1q9l B:1-111 [96282]
   Other proteins in same PDB: d1q9la1, d1q9la2, d1q9lb2, d1q9lc1, d1q9lc2, d1q9ld2
   part of Fab s25-2
   complexed with mg, zn

Details for d1q9lb1

PDB Entry: 1q9l, 2.28 Å

PDB Description: S25-2 Fab Unliganded 2

PDB Compounds: (B:) S25-2 Fab (IgG1k) heavy chain

SCOPe Domain Sequences for d1q9lb1:

Sequence; same for both SEQRES and ATOM records:

>d1q9lb1 b.1.1.1 (B:1-111) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 1 [TaxId: 10090]}
evklvesggglvqsggslrlscatsgftftdyymswvrqppgkalewlgfirnkangytt
eyspsvkgrftisrdnsqsilylqmntlraedsatyycardhdgyyerfsywgqgtlvtv
sa

Timeline for d1q9lb1:

• d1q9lb1 first appeared in SCOP 1.67
  
• d1q9lb1 appears in SCOP 1.75
  
• d1q9lb1 appears in SCOPe 2.02
  
• d1q9lb1 appears in the current release, SCOPe 2.08