SCOPe 2.06: Domain d1q7gb1: 1q7g B:2-150,B:341-359

Lineage for d1q7gb1 (1q7g B:2-150,B:341-359)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Homoserine dehydrogenase [51815] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51816] (4 PDB entries)
   Uniprot P31116

8. Domain d1q7gb1: 1q7g B:2-150,B:341-359 [96040]
   Other proteins in same PDB: d1q7ga2, d1q7gb2
   complexed with na, nho

Details for d1q7gb1

PDB Entry: 1q7g, 2.6 Å

PDB Description: Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline

PDB Compounds: (B:) homoserine dehydrogenase

SCOPe Domain Sequences for d1q7gb1:

Sequence; same for both SEQRES and ATOM records:

>d1q7gb1 c.2.1.3 (B:2-150,B:341-359) Homoserine dehydrogenase {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
stkvvnvavigagvvgsafldqllamkstitynlvllaeaersliskdfsplnvgsdwka
alaasttktlplddliahlktspkpvilvdntssayiagfytkfvengisiatpnkkafs
sdlatwkalfsnkptngfvyheatvgaglXaavtaagvlgdvikiaqrl

Timeline for d1q7gb1:

• d1q7gb1 first appeared in SCOP 1.67
  
• d1q7gb1 appears in SCOPe 2.05
  
• d1q7gb1 appears in SCOPe 2.07
  
• d1q7gb1 appears in the current release, SCOPe 2.08