SCOPe 2.05: Domain d1pzea1: 1pze A:14-163

Lineage for d1pzea1 (1pze A:14-163)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)

6. Protein Lactate dehydrogenase [51859] (17 species)

7. Species Toxoplasma gondii [TaxId:5811] [102166] (5 PDB entries)

8. Domain d1pzea1: 1pze A:14-163 [95415]
   Other proteins in same PDB: d1pzea2

Details for d1pzea1

PDB Entry: 1pze, 1.95 Å

PDB Description: T.gondii LDH1 apo form

PDB Compounds: (A:) lactate dehydrogenase

SCOPe Domain Sequences for d1pzea1:

Sequence, based on SEQRES records:

>d1pzea1 c.2.1.5 (A:14-163) Lactate dehydrogenase {Toxoplasma gondii [TaxId: 5811]}
palvqrrkkvamigsgmiggtmgylcalreladvvlydvvkgmpegkaldlshvtsvvdt
nvsvraeysyeaaltgadcvivtagltkvpgkpdsewsrndllpfnskiireigqnikky
cpktfiivvtnpldcmvkvmceasgvptnmicgm

Sequence, based on observed residues (ATOM records):

>d1pzea1 c.2.1.5 (A:14-163) Lactate dehydrogenase {Toxoplasma gondii [TaxId: 5811]}
palvqrrkkvamigsgmiggtmgylcalreladvvlydvvkgmpegkaldlshvtsvvdt
nvsvraeysyeaaltgadcvivtagltkvpgsewsrndllpfnskiireigqnikkycpk
tfiivvtnpldcmvkvmceasgvptnmicgm

Timeline for d1pzea1:

• d1pzea1 first appeared in SCOP 1.67
  
• d1pzea1 appears in SCOPe 2.04
  
• d1pzea1 appears in SCOPe 2.06
  
• d1pzea1 appears in the current release, SCOPe 2.08