Lineage for d1p2ce1 (1p2c E:1201-1313)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 781544Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)
  6. 781740Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 782204Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (152 PDB entries)
    Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E
    SQ NA # humanized antibody
    Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor
    Uniprot P01750 20-116 #
    HV06_MOUSE Ig heavy chain V region 102 precursor
    Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E ! SQ NA # humanized antibody ! Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor ! Uniprot P01750 20-116 # ! HV06_MOUSE Ig heavy chain V region 102 precursor
  8. 782240Domain d1p2ce1: 1p2c E:1201-1313 [93922]
    Other proteins in same PDB: d1p2ca1, d1p2ca2, d1p2cb2, d1p2cc_, d1p2cd1, d1p2cd2, d1p2ce2, d1p2cf_
    part of anti-lysozyme Fab F10.6.6

Details for d1p2ce1

PDB Entry: 1p2c (more details), 2 Å

PDB Description: crystal structure analysis of an anti-lysozyme antibody
PDB Compounds: (E:) heavy chain VH+CH1 anti-lysozyme antibody F10.6.6

SCOP Domain Sequences for d1p2ce1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1p2ce1 b.1.1.1 (E:1201-1313) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
evqlqesgaelmkpgasvkisckatgytfttywiewikqrpghslewigeilpgsdstyy
nekvkgkvtftadassntaymqlssltsedsavyycargdgfyvywgqgttlt

SCOP Domain Coordinates for d1p2ce1:

Click to download the PDB-style file with coordinates for d1p2ce1.
(The format of our PDB-style files is described here.)

Timeline for d1p2ce1: