Lineage for d1owha_ (1owh A:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 952974Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 952975Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 953177Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)
  6. 954489Protein Urokinase-type plasminogen activator (LMW U-PA), catalytic domain [50586] (1 species)
  7. 954490Species Human (Homo sapiens) [TaxId:9606] [50587] (52 PDB entries)
    Uniprot P00749 156-178,179-424
  8. 954496Domain d1owha_: 1owh A: [93643]
    complexed with 239, so4

Details for d1owha_

PDB Entry: 1owh (more details), 1.61 Å

PDB Description: substituted 2-naphthamidine inhibitors of urokinase
PDB Compounds: (A:) urokinase-type plasminogen activator

SCOPe Domain Sequences for d1owha_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1owha_ b.47.1.2 (A:) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
iiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
clpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irsht

SCOPe Domain Coordinates for d1owha_:

Click to download the PDB-style file with coordinates for d1owha_.
(The format of our PDB-style files is described here.)

Timeline for d1owha_: