Lineage for d1oita_ (1oit A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (400 PDB entries)
    Uniprot P24941
  8. 2542974Domain d1oita_: 1oit A: [93075]
    complexed with hdt

Details for d1oita_

PDB Entry: 1oit (more details), 1.6 Å

PDB Description: imidazopyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation
PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d1oita_:

Sequence, based on SEQRES records: (download)

>d1oita_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
nfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnhpn
ivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglsfchshr
vlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyyst
avdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpk
warqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d1oita_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
nfqkvekigegtygvvykarnklgevvalkkitaireisllkelnhpnivklldvihten
klylvfeflhqdlkkfmdasaltgiplpliksylfqllqglsfchshrvlhrdlkpqnll
integaikladfglaravvtlwyrapeillgckyystavdiwslgcifaemvtrralfpg
dseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsq
mlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d1oita_:

Click to download the PDB-style file with coordinates for d1oita_.
(The format of our PDB-style files is described here.)

Timeline for d1oita_: