Lineage for d1ohqa_ (1ohq A:)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1287638Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1287642Species Engineered (including hybrid species) [88562] (68 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # humanized antibody ! SQ NA # Humanized antibody ! SQ NA # engineered antibody
  8. 1287653Domain d1ohqa_: 1ohq A: [93027]
    soluble VH Hel4, resistant to aggregation

Details for d1ohqa_

PDB Entry: 1ohq (more details), 2 Å

PDB Description: crystal structure of hel4, a soluble human vh antibody domain resistant to aggregation
PDB Compounds: (A:) immunoglobulin

SCOPe Domain Sequences for d1ohqa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ohqa_ b.1.1.1 (A:) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}

SCOPe Domain Coordinates for d1ohqa_:

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Timeline for d1ohqa_:

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