SCOPe 2.01: Domain d1of2a2: 1of2 A:1-181

Lineage for d1of2a2 (1of2 A:1-181)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (1 family)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (27 species)

7. Species Human (Homo sapiens), HLA-B27 [TaxId:9606] [54471] (8 PDB entries)
   Uniprot P03989 25-300

8. Domain d1of2a2: 1of2 A:1-181 [92809]
   Other proteins in same PDB: d1of2a1, d1of2b_
   complexed with gol, mn

Details for d1of2a2

PDB Entry: 1of2, 2.2 Å

PDB Description: crystal structure of hla-b*2709 complexed with the vasoactive intestinal peptide type 1 receptor (vipr) peptide (residues 400-408)

PDB Compounds: (A:) human lymphocyte antigen hla-b27

SCOPe Domain Sequences for d1of2a2:

Sequence; same for both SEQRES and ATOM records:

>d1of2a2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-B27 [TaxId: 9606]}
gshsmryfhtsvsrpgrgeprfitvgyvddtlfvrfdsdaaspreeprapwieqegpeyw
dretqickakaqtdredlrtllryynqseagshtlqnmygcdvgpdgrllrgyhqhaydg
kdyialnedlsswtaadtaaqitqrkweaarvaeqlraylegecvewlrrylengketlq
r

Timeline for d1of2a2:

• d1of2a2 first appeared in SCOP 1.67
  
• d1of2a2 appears in SCOP 1.75
  
• d1of2a2 appears in SCOPe 2.02
  
• d1of2a2 appears in the current release, SCOPe 2.08