SCOPe 2.01: Domain d1nwsc1: 1nws C:22-260,C:329-383

Lineage for d1nwsc1 (1nws C:22-260,C:329-383)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.5: Type II chitinase [51534] (15 proteins)
   glycosylase family 18

6. Protein Chitinase-3 like protein 1 (GP-39, YKL-40) [89482] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89483] (7 PDB entries)

8. Domain d1nwsc1: 1nws C:22-260,C:329-383 [92257]
   Other proteins in same PDB: d1nwsa2, d1nwsb2, d1nwsc2, d1nwsd2

Details for d1nwsc1

PDB Entry: 1nws, 2.7 Å

PDB Description: crystal structure of human cartilage gp39 (hc-gp39) in complex with chitobiose

PDB Compounds: (C:) chitinase-3 like protein 1

SCOPe Domain Sequences for d1nwsc1:

Sequence; same for both SEQRES and ATOM records:

>d1nwsc1 c.1.8.5 (C:22-260,C:329-383) Chitinase-3 like protein 1 (GP-39, YKL-40) {Human (Homo sapiens) [TaxId: 9606]}
yklvcyytswsqyregdgscfpdaldrflcthiiysfanisndhidtwewndvtlygmln
tlknrnpnlktllsvggwnfgsqrfskiasntqsrrtfiksvppflrthgfdgldlawly
pgrrdkqhfttlikemkaefikeaqpgkkqlllsaalsagkvtidssydiakisqhldfi
simtydfhgawrgttghhsplfrgqedaspdrfsntdyavgymlrlgapasklvmgiptX
ddqesvkskvqylkdrqlagamvwaldlddfqgsfcgqdlrfpltnaikdalaat

Timeline for d1nwsc1:

• d1nwsc1 first appeared in SCOP 1.67
  
• d1nwsc1 appears in SCOP 1.75
  
• d1nwsc1 appears in SCOPe 2.02
  
• d1nwsc1 appears in the current release, SCOPe 2.08