SCOP 1.75: Domain d1mrya_: 1mry A:

Lineage for d1mrya_ (1mry A:)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Pkb kinase (Akt-2) [82791] (1 species)
   AGC group; RAC/Akt subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [82792] (14 PDB entries)

8. Domain d1mrya_: 1mry A: [91451]

Details for d1mrya_

PDB Entry: 1mry, 2.8 Å

PDB Description: crystal structure of an inactive akt2 kinase domain

PDB Compounds: (A:) RAC-beta serine/threonine kinase

SCOP Domain Sequences for d1mrya_:

Sequence, based on SEQRES records:

>d1mrya_ d.144.1.7 (A:) Pkb kinase (Akt-2) {Human (Homo sapiens) [TaxId: 9606]}
kvtmndfdylkllgkgtfgkvilvrekatgryyamkilrkeviiakdevahtvtesrvlq
ntrhpfltalkyafqthdrlcfvmeyanggelffhlsrervfteerarfygaeivsaley
lhsrdvvyrdiklenlmldkdghikitdfglckegisdgatmktfcgtpeylapevledn
dygravdwwglgvvmyemmcgrlpfynqdherlfelilmeeirfprtlspeaksllagll
kkdpkqrlgggpsdakevmehrfflsinwqdvvqkkllppfkpqvtsevdtryfd

Sequence, based on observed residues (ATOM records):

>d1mrya_ d.144.1.7 (A:) Pkb kinase (Akt-2) {Human (Homo sapiens) [TaxId: 9606]}
kvtmndfdylkllgkgtfgkvilvrekatgryyamkilrkeviirvlqntrhpfltalky
afqthdrlcfvmeyanggelffhlsrervfteerarfygaeivsaleylhsrdvvyrdik
lenlmldkdghikitdfglccgtpeylapevledndygravdwwglgvvmyemmcgrlpf
ynqdherlfelilmeeirfprtlspeaksllagllkkdpkqrlgggpsdakevmehrffl
sinwqdvvqkkllppfkpqvtsevdtryfd

Timeline for d1mrya_:

• d1mrya_ first appeared in SCOP 1.67
  
• d1mrya_ appears in SCOP 1.73
  
• d1mrya_ appears in SCOPe 2.01
  
• d1mrya_ appears in the current release, SCOPe 2.08