SCOP 1.73: Domain d1mqba_: 1mqb A:

Lineage for d1mqba_ (1mqb A:)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein epha2 receptor tyrosine kinase [103294] (1 species)
   PTK group; Eph/Elk/Eck subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [103295] (1 PDB entry)

8. Domain d1mqba_: 1mqb A: [91392]

Details for d1mqba_

PDB Entry: 1mqb, 2.3 Å

PDB Description: Crystal Structure of Ephrin A2 (ephA2) Receptor Protein Kinase

PDB Compounds: (A:) Ephrin type-A receptor 2

SCOP Domain Sequences for d1mqba_:

Sequence, based on SEQRES records:

>d1mqba_ d.144.1.7 (A:) epha2 receptor tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
tteihpscvtrqkvigagefgevykgmlktssgkkevpvaiktlkagytekqrvdflgea
gimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgia
agmkylanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatyttsggkipirwt
apeaisyrkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgfrlptpmdcps
aiyqlmmqcwqqerarrpkfadivsildklirapdslktladf

Sequence, based on observed residues (ATOM records):

>d1mqba_ d.144.1.7 (A:) epha2 receptor tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
tteihpscvtrqkvigagefgevykgmlktkkevpvaiktlkagytekqrvdflgeagim
gqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgiaagm
kylanmnyvhrdlaarnilvnsnlvckvsdfglkipirwtapeaisyrkftsasdvwsfg
ivmwevmtygerpywelsnhevmkaindgfrlptpmdcpsaiyqlmmqcwqqerarrpkf
adivsildklirapdslktladf

Timeline for d1mqba_:

• d1mqba_ first appeared in SCOP 1.67
  
• d1mqba_ appears in SCOP 1.71
  
• d1mqba_ appears in SCOP 1.75
  
• d1mqba_ appears in the current release, SCOPe 2.08