SCOPe 2.06: Domain d1moxb4: 1mox B:481-501

Lineage for d1moxb4 (1mox B:481-501)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.9: Growth factor receptor domain [57184] (2 families)

5. Family g.3.9.1: Growth factor receptor domain [57185] (10 proteins)
   Pfam PF00757; Pfam PF14843; Pfam PF15913

6. Protein EGF receptor Cys-rich domains [82887] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82888] (6 PDB entries)

8. Domain d1moxb4: 1mox B:481-501 [91379]
   Other proteins in same PDB: d1moxa1, d1moxa2, d1moxb1, d1moxb2, d1moxc_, d1moxd_
   complexed with TGF-alpha
   complexed with cd, cl, nag, pt

Details for d1moxb4

PDB Entry: 1mox, 2.5 Å

PDB Description: crystal structure of human epidermal growth factor receptor (residues 1-501) in complex with tgf-alpha

PDB Compounds: (B:) Epidermal growth factor receptor

SCOPe Domain Sequences for d1moxb4:

Sequence; same for both SEQRES and ATOM records:

>d1moxb4 g.3.9.1 (B:481-501) EGF receptor Cys-rich domains {Human (Homo sapiens) [TaxId: 9606]}
vchalcspegcwgpeprdcvs

Timeline for d1moxb4:

• d1moxb4 first appeared in SCOP 1.67
  
• d1moxb4 appears in SCOPe 2.05
  
• d1moxb4 appears in SCOPe 2.07
  
• d1moxb4 appears in the current release, SCOPe 2.08