Lineage for d1moxa3 (1mox A:163-311)

  1. Root: SCOPe 2.05
  2. 1959977Class g: Small proteins [56992] (92 folds)
  3. 1960255Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. 1961098Superfamily g.3.9: Growth factor receptor domain [57184] (2 families) (S)
  5. 1961099Family g.3.9.1: Growth factor receptor domain [57185] (9 proteins)
  6. 1961100Protein EGF receptor Cys-rich domains [82887] (1 species)
  7. 1961101Species Human (Homo sapiens) [TaxId:9606] [82888] (6 PDB entries)
  8. 1961105Domain d1moxa3: 1mox A:163-311 [91374]
    Other proteins in same PDB: d1moxa1, d1moxa2, d1moxb1, d1moxb2, d1moxc_, d1moxd_
    complexed with TGF-alpha
    complexed with cd, cl, nag, pt

Details for d1moxa3

PDB Entry: 1mox (more details), 2.5 Å

PDB Description: Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha
PDB Compounds: (A:) Epidermal growth factor receptor

SCOPe Domain Sequences for d1moxa3:

Sequence, based on SEQRES records: (download)

>d1moxa3 g.3.9.1 (A:163-311) EGF receptor Cys-rich domains {Human (Homo sapiens) [TaxId: 9606]}
cqkcdpscpngscwgageencqkltkiicaqqcsgrcrgkspsdcchnqcaagctgpres
dclvcrkfrdeatckdtcpplmlynpttyqmdvnpegkysfgatcvkkcprnyvvtdhgs
cvracgadsyemeedgvrkckkcegpcrk

Sequence, based on observed residues (ATOM records): (download)

>d1moxa3 g.3.9.1 (A:163-311) EGF receptor Cys-rich domains {Human (Homo sapiens) [TaxId: 9606]}
cqkcdpscpngscwgageencqkltkiicaqqcsgrcrgkspsdcchnqcaagctgpres
dclvcrkfrdeatckdtcpplmlynpttyqmdvnpegkysfgatcvkkcprnyvvtdhgs
cvracgadsyemeedgvrkckkcgpcrk

SCOPe Domain Coordinates for d1moxa3:

Click to download the PDB-style file with coordinates for d1moxa3.
(The format of our PDB-style files is described here.)

Timeline for d1moxa3: