SCOP 1.71: Domain d1hkma1: 1hkm A:22-266,A:335-386

Lineage for d1hkma1 (1hkm A:22-266,A:335-386)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (32 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (13 families)

5. Family c.1.8.5: Type II chitinase [51534] (14 proteins)
   glycosylase family 18

6. Protein Chitotriosidase [82251] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82252] (8 PDB entries)

8. Domain d1hkma1: 1hkm A:22-266,A:335-386 [90636]
   Other proteins in same PDB: d1hkma2
   complexed with ali, naa

Details for d1hkma1

PDB Entry: 1hkm, 2.55 Å

PDB Description: high resolution crystal structure of human chitinase in complex with demethylallosamidin

SCOP Domain Sequences for d1hkma1:

Sequence; same for both SEQRES and ATOM records:

>d1hkma1 c.1.8.5 (A:22-266,A:335-386) Chitotriosidase {Human (Homo sapiens)}
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeqsgaaaslnvdaavqqwlqkgtpaskli
lgmptXddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtlrqels

Timeline for d1hkma1:

• d1hkma1 first appeared in SCOP 1.67
  
• d1hkma1 appears in SCOP 1.69
  
• d1hkma1 appears in SCOP 1.73
  
• d1hkma1 appears in the current release, SCOPe 2.08