SCOPe 2.06: Family f.37.1.1: ABC transporter transmembrane region

Lineage for Family f.37.1.1: ABC transporter transmembrane region

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.37: ABC transporter transmembrane region [90122] (1 superfamily)
   multihelical; complex architecture with several transmembrane helices

4. Superfamily f.37.1: ABC transporter transmembrane region [90123] (2 families)
   automatically mapped to Pfam PF00664

5. Family f.37.1.1: ABC transporter transmembrane region [90124] (3 proteins)

Proteins:

1. Multidrug resistance ABC transporter MsbA, N-terminal domain [90125] (1 species)
   a low-resolution structure of the E.coli MsbA in an open conformation is also available (f.35.1.1)

   • Species Salmonella typhimurium [TaxId:90371] [161075] (3 PDB entries)
     Uniprot P63359 10-328

2. P-glycoprotein (P-gp) multidrug resistance protein, transmembrane region [310789] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [311046] (1 PDB entry)

3. Putative multidrug export ATP-binding/permease protein SAV1866 [144087] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [224951] (1 PDB entry)

   2. Species Staphylococcus aureus [TaxId:1280] [144088] (2 PDB entries)
      Uniprot Q99T13 1-323

More info for Family f.37.1.1: ABC transporter transmembrane region

Timeline for Family f.37.1.1: ABC transporter transmembrane region:

• Family f.37.1.1: ABC transporter transmembrane region first appeared in SCOP 1.65, called Family f.37.1.1: Multidrug resistance ABC transporter MsbA, N-terminal domain
  
• Family f.37.1.1: ABC transporter transmembrane region appears in SCOPe 2.05
  
• Family f.37.1.1: ABC transporter transmembrane region appears in SCOPe 2.07
  
• Family f.37.1.1: ABC transporter transmembrane region appears in the current release, SCOPe 2.08